Epilepsy Clinical Trials


Cannabidiol Oral Solution in Pediatric Participants With Treatment-Resistant Childhood Absence Seizures

Condition:   Childhood Absence Epilepsy
Intervention:   Drug: Cannabidiol Oral Solution
Sponsor:   INSYS Therapeutics Inc
Recruiting

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A Study to Investigate the Efficacy and Safety of ZX008 (Fenfluramine Hydrochloride) as an Adjunctive Therapy in Children and Adults With Lennox-Gastaut Syndrome

Condition:   Lennox Gastaut Syndrome
Interventions:   Drug: ZX008 02 and 0.8 mg/kg/day;   Other: Placebo
Sponsor:   Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc.
Recruiting

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Stereotactic Laser Ablation for Temporal Lobe Epilepsy

Condition:   Temporal Lobe Epilepsy
Intervention:   Device: Visualase MRI-Guided Laser Ablation
Sponsor:   Medtronic Navigation, Inc.
Recruiting

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Study to Investigate Safety and Tolerability of Intravenous Lacosamide in Children.

Condition:   Epilepsy
Intervention:   Drug: Lacosamide
Sponsor:   UCB BIOSCIENCES, Inc.
Recruiting

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Tumor Related Epilepsy

Conditions:   Epilepsy;   Cancer;   Brain Neoplasm
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting

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Efficacy and Safety of Lacosamide as Adjunctive Therapy in Subjects ?1 Month to

Condition:   Epilepsy With Partial-onset Seizures
Interventions:   Drug: Lacosamide;   Other: Placebo
Sponsor:   UCB BIOSCIENCES, Inc.
Recruiting

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Medium Chain Triglycerides as an Adjunct to the Modified Atkins Diet for Women With Catamenial Epilepsy

Conditions:   Epilepsy;   Seizure;   Catamenial Epilepsy;   Medically Resistant Epilepsy;   Medically Resistant Seizures
Intervention:   Dietary Supplement: betaquik®
Sponsors:   Johns Hopkins University;   Vitaflo International, Ltd
Recruiting

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A Study to Assess the Safety and Efficacy of Lacosamide Versus Placebo (a Pill Without Active Medication) in Patients With Idiopathic Generalised Epilepsy Who Are Already Taking Anti-epileptic Medications

Condition:   Epilepsy
Interventions:   Drug: Lacosamide Tablet;   Drug: Lasosamide Oral Solution;   Other: Placebo Tablet;   Other: Placebo Oral Solution
Sponsors:   UCB BIOSCIENCES, Inc.;   Pharmaceutical Research Associates
Recruiting

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Genetic Characterization of Movement Disorders and Dementias

Conditions:   Ataxia;   Dystonia;   Parkinson's Disease;   Amyotrophic Lateral Sclerosis;   Corticobasal Degeneration;   Multiple System Atrophy;   Alzheimer's Disease;   Lewy Body Dementia;   Parkinson Disease-Dementia;   Dentatorubral-pallidoluysian Atrophy;   Creutzfeldt-Jakob Disease and Fatal Familial Insomnia;   Fragile X-associated Tremor/Ataxia Syndrome;   Krabbe's Disease;   Niemann-Pick Disease, Type C;   Neuronal Ceroid Lipofuscinosis
Intervention:  
Sponsor:   National Institute on Aging (NIA)
Recruiting

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A Safety, Efficacy and Tolerability Trial of Pregabalin as Add-On Treatment in Pediatric and Adult Subjects With Primary Generalized Tonic-Clonic (i.e., Grand Mal) Seizures.

Condition:   Generalized Tonic Clonic Seizures
Interventions:   Drug: Pregabalin Dose Level 1;   Drug: Pregabalin Dose Level 2;   Drug: Placebo
Sponsor:   Pfizer
Recruiting

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Neurobiology of Psychogenic Movement Disorder and Non-Epileptic Seizures

Conditions:   Psycogenic Movement Disorders;   Non-epileptic Seizures
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting

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Evaluation and Treatment of Neurosurgical Disorders

Condition:   Neurologic Disorders
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting

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Study of Specimens Obtained During Epilepsy Surgery

Condition:   Epilepsy
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting

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