Epilepsy Clinical Trials


A Pediatric Drug Study to Determine the Long-term Safety and Tolerability in Children and Adolescents (4-17 Years in Age) Taking the Drug

Condition:   Epilepsy
Intervention:   Drug: Eslicarbazepine acetate
Sponsor:   Sunovion
Recruiting - verified September 2017

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A Study to Assess the Efficacy and Safety of Brivaracetam as Treatment for Increased Seizure Activity in an Epilepsy Monitoring Unit Setting

Condition:   Epilepsy
Interventions:   Drug: Brivaracetam;   Drug: Lorazepam
Sponsor:   UCB Biopharma S.P.R.L.
Recruiting - verified September 2017

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Adapting Project UPLIFT for Blacks in Georgia

Condition:   Depressive Symptoms
Intervention:   Behavioral: Project UPLIFT
Sponsors:   Morehouse School of Medicine;   Emory University
Recruiting - verified September 2017

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A Two-Part Study to Investigate the Dose-Ranging Safety and Pharmacokinetics, Followed by the Efficacy and Safety of ZX008 (Fenfluramine Hydrochloride) Oral Solution as an Adjunctive Therapy in Children ?2 Years Old and Young Adults With Dravet Syndrome

Condition:   Dravet Syndrome
Interventions:   Drug: ZX008 - 0.2 mg/kg/day;   Drug: ZX008 - 0.4 mg/kg/day;   Drug: ZX008 - 20 mg/day maximum dose;   Drug: Matching Placebo
Sponsor:   Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc.
Recruiting - verified September 2017

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Pharmacokinetic Study With an Oral Suspension of Perampanel as Adjunctive Therapy in Pediatric Subjects With Epilepsy

Condition:   Epilepsy
Intervention:   Drug: perampanel
Sponsor:   Eisai Inc.
Recruiting - verified September 2017

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A Trial of Two Fixed Doses of ZX008 (Fenfluramine HCl) in Children and Young Adults With Dravet Syndrome

Conditions:   Dravet Syndrome;   Seizure Disorder
Interventions:   Drug: ZX008 (Fenfluramine Hydrochloride);   Drug: Matching Placebo
Sponsor:   Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc.
Recruiting - verified September 2017

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Carisbamate in Adult & Pediatric Subjects With Lennox-Gastaut Syndrome

Condition:   Lennox Gastaut Syndrome
Intervention:   Drug: Carisbamate
Sponsor:   SK Life Science, Inc.
Recruiting

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Improving Patient Communication About SUDEP

Conditions:   SUDEP;   Epilepsy
Intervention:   Behavioral: CHICA SUDEP module
Sponsors:   Indiana University;   Child Neurology Foundation;   Greenwich Biosciences
Recruiting

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Clinical Utility of the SPEAC® System: A Case Series

Condition:   Epilepsy
Intervention:   Device: SPEAC System
Sponsor:   Brain Sentinel
Recruiting

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Novel Helmet Design in Patients With Seizures

Conditions:   Drug Resistant Epilepsy;   Drop Seizures;   Generalized Tonic Clonic Seizure;   Complex Partial Seizure;   Fall Due to Seizure
Intervention:   Device: Hövding inflatable helmet
Sponsors:   Michael A. Gelfand, MD, PhD;   Epilepsy Foundation
Recruiting

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Phase II Trial of Seizure Prophylaxis in Suspected Primary Glioma Patients Undergoing Craniotomy

Conditions:   Glioma;   Glioma of Brain;   Brain Tumor
Interventions:   Drug: Lacosamide;   Drug: Levetiracetam
Sponsor:   Duke University
Not yet recruiting

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A Study to Assess the Efficacy, Safety, and Tolerability of Cannabidiol Oral Solution With Vigabatrin as Initial Therapy in Participants With Infantile Spasms

Condition:   Infantile Spasm
Interventions:   Drug: Cannabidiol Oral Solution;   Drug: Placebo;   Drug: Vigabatrin
Sponsor:   INSYS Therapeutics Inc
Recruiting

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Study to Test the Efficacy and Safety of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adults With Drug-resistant Epilepsy

Conditions:   Drug-resistant Epilepsy;   Focal-Onset Seizures
Interventions:   Drug: Padsevonil;   Other: Placebo
Sponsor:   UCB Biopharma S.P.R.L.
Recruiting

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Long-Term Safety of Pharmaceutical Grade Synthetic Cannabidiol Oral Solution in Pediatric Participants With Treatment-Resistant Childhood Absence Seizures

Condition:   Childhood Absence Epilepsy
Intervention:   Drug: Cannabidiol Oral Solution
Sponsor:   INSYS Therapeutics Inc
Recruiting

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