Colorectal Cancer (CRC) Clinical Trials


Comparing Interventions to Increase Colorectal Cancer Screening

Condition:   Colorectal Cancer
Interventions:   Behavioral: DVD;   Behavioral: Patient Navigation
Sponsors:   Indiana University;   Patient-Centered Outcomes Research Institute;   Ohio State University
Not yet recruiting - verified June 2017

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Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*1101 Patients

Conditions:   Pancreatic Cancer;   Gastric Cancer;   Gastrointestinal Cancer;   Colon Cancer;   Rectal Cancer
Interventions:   Drug: Cyclophosphamide;   Drug: Fludarabine;   Biological: anti-KRAS G12V mTCR;   Drug: Aldesleukin
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting - verified June 6, 2017

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Phase I Study of Oral STAT3 Inhibitor, C188-9, in Patients With Advanced Cancers

Conditions:   Breast Cancer;   Head and Neck Squamous Cell Carcinoma;   Non Small Cell Lung Cancer;   Hepatocellular Cancer;   Colorectal Cancer;   Gastric Adenocarcinoma;   Melanoma;   Advanced Cancer
Intervention:   Drug: C188-9
Sponsors:   StemMed, Ltd., USA;   M.D. Anderson Cancer Center
Not yet recruiting - verified June 2017

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A Study of BMS-813160 in Combination With Chemotherapy or Nivolumab in Patients With Advanced Solid Tumors

Conditions:   Colorectal Cancer;   Pancreatic Cancer
Interventions:   Drug: BMS-813160;   Biological: Nivolumab;   Drug: Nab-paclitaxel;   Drug: Gemcitabine;   Drug: 5-fluorouracil (5-FU);   Drug: Leucovorin;   Drug: Irinotecan
Sponsor:   Bristol-Myers Squibb
Not yet recruiting - verified June 2017

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Financial Incentives to Increase Colorectal Cancer Screening in Priority Populations

Condition:   Colorectal Cancer
Interventions:   Behavioral: Auto Mailing Plus Money;   Behavioral: Auto Mailing Plus Lottery
Sponsors:   Group Health Cooperative;   University of Michigan;   University of Texas
Recruiting - verified June 2017

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Standard of Care Alone or in Combination With Ad-CEA Vaccine and Avelumab in People With Previously Untreated Metastatic Colorectal Cancer QUILT-2.004

Condition:   Colorectal Cancer
Interventions:   Drug: Avelumab;   Biological: Ad-CEA vaccine;   Drug: Bevacizumab;   Drug: 5-FU;   Drug: Leucovorin;   Drug: Oxaliplatin;   Drug: Capecitabine
Sponsor:   National Cancer Institute (NCI)
Recruiting - verified March 13, 2017

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A Study of SC-006 in Subjects With Advanced Cancer

Condition:   Colorectal Cancer (CRC)
Intervention:   Drug: SC-006
Sponsor:   AbbVie
Recruiting - verified June 2017

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Hereditary Gastric Cancer Syndromes: An Integrated Genomic and Clinicopathologic Study of the Predisposition to Gastric Cancer

Conditions:   Stomach Neoplasms;   Stomach Cancer;   Familial Cancer;   Fundic Gland Polyposis;   Li-Fraumeni Syndrome;   Lynch Syndrome;   Peutz-Jeghers Syndrome
Intervention:  
Sponsor:   National Cancer Institute (NCI)
Recruiting - verified January 23, 2017

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Combination Chemotherapy, Bevacizumab, and/or Atezolizumab in Treating Patients With Microsatellite Instability-High Metastatic Colorectal Cancer

Conditions:   Colorectal Adenocarcinoma;   High-Frequency Microsatellite Instability;   Stage IV Colorectal Cancer;   Stage IVA Colorectal Cancer;   Stage IVB Colorectal Cancer
Interventions:   Drug: Atezolizumab;   Biological: Bevacizumab;   Drug: Fluorouracil;   Other: Laboratory Biomarker Analysis;   Drug: Leucovorin Calcium;   Drug: Oxaliplatin;   Other: Quality-of-Life Assessment
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting - verified May 2017

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Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair or Microsatellite Instability

Conditions:   Colon Adenocarcinoma;   DNA Repair Disorder;   Lynch Syndrome;   Microsatellite Instability;   Stage IIIA Colon Cancer;   Stage IIIB Colon Cancer;   Stage IIIC Colon Cancer
Interventions:   Drug: Atezolizumab;   Drug: Fluorouracil;   Other: Laboratory Biomarker Analysis;   Drug: Leucovorin Calcium;   Drug: Oxaliplatin;   Other: Quality-of-Life Assessment
Sponsor:   National Cancer Institute (NCI)
Not yet recruiting - verified May 2017

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A Safety Study of SGN-2FF for Patients With Advanced Solid Tumors

Conditions:   Non-small Cell Lung Cancer;   Renal Cell Cancer;   Breast Cancer;   Bladder Cancer;   Head and Neck Cancer;   Colorectal Cancer
Intervention:   Drug: SGN-2FF
Sponsor:   Seattle Genetics, Inc.
Recruiting - verified June 2017

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Durvalumab and Tremelimumab With or Without High or Low-Dose Radiation Therapy in Treating Patients With Metastatic Colorectal or Non-small Cell Lung Cancer

Conditions:   Recurrent Colorectal Carcinoma;   Recurrent Non-Small Cell Lung Carcinoma;   Stage IV Non-Small Cell Lung Cancer;   Stage IVA Colorectal Cancer;   Stage IVB Colorectal Cancer
Interventions:   Biological: Durvalumab;   Other: Laboratory Biomarker Analysis;   Radiation: Radiation Therapy;   Biological: Tremelimumab
Sponsor:   National Cancer Institute (NCI)
Recruiting - verified June 2017

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The Beans to Enrich the Gut Microbiome vs. Obesity's Negative Effects (BE GONE) Trial

Condition:   Colorectal Cancer Prevention
Interventions:   Other: Regular Diet;   Other: Navy Beans (Canned)
Sponsor:   M.D. Anderson Cancer Center
Recruiting - verified June 2017

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High Definition Single Cell Analysis in Colorectal Cancer

Conditions:   Metastatic Carcinoma in the Liver;   Stage IV Colorectal Cancer
Interventions:   Other: Biomarker Analysis;   Other: Cytology Specimen Collection Procedure
Sponsors:   University of Southern California;   National Cancer Institute (NCI)
Recruiting - verified June 2017

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Open-label, Single Arm Trial of BI 695502 in Patients With Previously Untreated Metastatic Colorectal Cancer

Condition:   Colorectal Neoplasms
Interventions:   Drug: BI 695502;   Drug: chemotherapy
Sponsor:   Boehringer Ingelheim
Recruiting - verified June 2017

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