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Tumor-fighting combination targets aggressive form of brain cancer

 8 months ago       109 Views

Researchers have paired a specialized diet and a tumor-fighting drug and found the non-toxic combination helps to destroy the two major cells found in an aggressive form of brain cancer, the team reports in the online edition of the Nature group journal Communications Biology.

The international team combined a calorie-restricted diet high in fat and low in carbohydrates with a tumor-inhibiting antibiotic and found the combination destroys cancer stem cells and mesenchymal cells, the two major cells found in glioblastoma, a fast-moving brain cancer that resists traditional treatment protocols.

The ketogenic diet and the antibiotic 6-diazo-5-oxo-L-norleucine - first characterized in 1956 and referred to as DON - offer a non-toxic therapeutic strategy that could be used to manage the deadly brain cancer, said Boston College Professor of Biology Thomas N. Seyfried, a lead author of the paper with Boston College Senior Research Scientist Purna Mukherjee.

Author: @DailyCupofYoga


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