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Research opens up new therapeutic area to better manage chronic inflammatory diseases

 10 months ago       105 Views

Atherosclerosis is a disease defined by the accumulation of fatty deposits called plaques inside the arteries. It is a leading cause of heart attacks and strokes. Despite treatments that address risk factors such as poor diet, up to 70 % of cardiovascular events are not prevented by current therapeutic procedures.

Recent research shows that immune cell responses contribute to atherosclerotic plaque progression. Meanwhile, studies in mice have indicated that poor diet can trigger an inflammatory state of the immune system over long periods due to an epigenetic mechanism. Epigenetics is a change in an organism caused by modifications in gene expression; such changes can be triggered by environmental factors.


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