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Parkinson's: Study reveals how cancer drug reduces toxic protein in brain

 1 year ago       136 Views

Loss of dopamine, a brain chemical that helps to control movement, is one of the main hallmarks of Parkinson's disease. Another is the presence in the brain of Lewy bodies containing toxic clumps of the protein alpha-synuclein.

The toxic alpha-synuclein clumps interfere with the brain's ability to use dopamine from the little pockets, or vesicles, that store it.

Researchers at Georgetown University Medical Center (GUMC) in Washington, DC, examined the effects of a single dose of nilotinib on the volunteers taking part in the trial. They found that it reduced the toxic alpha-synuclein that stops the brain from utilizing the dopamine in the vesicles.

Author: @DailyCupofYoga


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