Hemophilia

What is hemophilia?

Hemophilia is a rare, inherited (genetic) disorder in which your blood does not clot normally because it lacks sufficient blood-clotting proteins (clotting factors). Clotting factor is a protein in blood that controls bleeding. This can lead to spontaneous bleeding as well as bleeding following injuries or surgery. People with hemophilia do not bleed any faster than normal, but they can bleed for a longer time. The severity of hemophilia that a person has is determined by the amount of clotting factor in the blood. The lower the amount of the clotting factor, the more likely it is that bleeding will occur which can lead to serious health problems.
 
 
Types of hemophilia
They are classified according to which clotting factor is deficient:
 
  • Hemophilia A, the most common type caused by insufficient clotting factor VIII.
  • Hemophilia B, the second most common type caused by insufficient clotting factor IX.
  • Hemophilia C is caused by insufficient clotting factor XI.
 
 
 
Risk factors
 
  • Family history. Hemophilia is a sex-linked recessive trait. 
  • Being a male. Males are more at risk for inheriting hemophilia than females.
 
 
Diagnosis
Diagnosis for hemophilia requires taking a blood sample and measuring the level of clotting factor activity in the blood. Level of factor VIII activity is tested for diagnosing hemophilia A. Hemophilia B is diagnosed by measuring the level of factor IX activity. Hemophilia C diagnosis measures the level of factor XI activity
 
 
Prenatal diagnosis
 
  • Chorionic villus sampling (CVS) can detect hemophilia at 9 to 11 weeks.
  • Fetal blood sampling can detect hemophilia at 18 or more weeks.
 
 
Treatment
There is no cure yet for hemophilia, however with proper treatment and self-care, most hemophiliacs can maintain an active and productive lifestyle.
 
 
 
# HEMOPHILIA BY THE NUMBERS #
  • Roughly 1/3 of new diagnoses have no previous family history. 
  • Approximately 20,000 people with hemophilia in the US. 
  • Hemophilia A is 4x more common than hemophilia B.
  • An estimated 400,000 people worldwide are living with hemophilia. 
  • Only 25% receive adequate treatment.
  • About 1 in 10,000 people is born with hemophilia A. 
  • About 1 in 50,000 people is born with hemophilia B.
 
about hemophilia
 
 

Sources
  • "Hemophilia." Mayo Clinic. Mayo Foundation for Medical Education and Research, 26 Sept. 2014. Web. 21 May 2017.
  • "Hemophilia." Centers for Disease Control and Prevention. Centers for Disease Control and Prevention, 17 Apr. 2017. Web. 21 May 2017.
  • "Genes and Human Disease." WHO. World Health Organization, n.d. Web. 21 May 2017.
  • "Types of Bleeding Disorders." National Hemophilia Foundation. The National Hemophilia Foundation (NHF), 27 Feb. 2017. Web. 21 May 2017.
  • "What Is Hemophilia?" What Is Hemophilia? - World Federation of Hemophilia. World Federation of Hemophilia, n.d. Web. 21 May 2017.

 

From Our Blog: Bleeding Disorder Awareness Month

Bleeding disorder awareness month is meant to simply to educate others of the various bleeding disorders and and their symptoms. Bleeding disorders can be inherited or acquired. Bleeding disorders are a group of medical conditions that result when the blood cannot clot properly. This can lead to abnormal bleeding inside and out of the body.
 
bleeding disorders awareness month
 

 

NOTE: The information on this page and any information found on healtheo360 is not a substitution for professional medical advice, diagnosis or treatment. If you think you may have a medical emergency, CALL 911 immediately. See additional information about our Terms & Conditions.