Glioma Clinical Trials


Combination of PVSRIPO and Atezolizumab for Adults With Recurrent Malignant Glioma

Condition:   Malignant Glioma
Interventions:   Biological: PVSRIPO;   Drug: Atezolizumab
Sponsors:   Darell D. Bigner, MD, PhD;   Istari Oncology, Inc.;   Genentech, Inc.
Not yet recruiting

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Remote Brain Microhaemorrhages May Predict Haematoma in Glioma Patients Treated With Radiation Therapy

Condition:   Glioma
Intervention:   Diagnostic Test: Cere
Sponsor:   Fondation Ophtalmologique Adolphe de Rothschild
Completed

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Determining Dose of Regadenoson Most Likely to Transiently Alter the Integrity of the Blood-Brain Barrier in Patients With High Grade Gliomas

Conditions:   High Grade Glioma;   Anaplastic Astrocytoma;   Anaplastic Oligodendroglioma;   Glioblastoma
Interventions:   Drug: Regadenoson 0.05mg;   Drug: Regadensoson 0.1mg;   Drug: Regadensoson 0.2mg;   Drug: Regadensoson 0.4mg;   Drug: Regadensoson 0.7mg;   Drug: Regadensoson 1.0mg;   Drug: Regadensoson 1.4mg
Sponsors:   Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins;   National Cancer Institute (NCI)
Not yet recruiting

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Organoids Derived From Induced-Pluripotent Stem Cells (iPS) From Patients With High Grade Astrocytoma

Condition:   Glioma
Intervention:   Biological: Blood sample
Sponsor:   Assistance Publique Hopitaux De Marseille
Recruiting

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Anti-Cancer Effects of Carvedilol With Standard Treatment in Glioblastoma and Response of Peripheral Glioma Circulating Tumor Cells

Conditions:   Glioblastoma;   Glioblastoma Multiforme
Intervention:   Drug: Carvedilol
Sponsors:   West Virginia University;   NovoCure Ltd.;   West Virginia Clinical and Translational Science Institute
Not yet recruiting

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Study of Binimetinib With Encorafenib in Adults With Recurrent BRAF V600-Mutated HGG

Conditions:   High Grade Glioma;   BRAF V600E;   BRAF V600K;   Anaplastic Astrocytoma;   Anaplastic Pleomorphic Xanthoastrocytoma;   Gliosarcoma;   Glioblastoma
Interventions:   Drug: Encorafenib;   Drug: Binimetinib;   Biological: Research Bloods;   Biological: Tumor Tissue
Sponsors:   Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins;   National Cancer Institute (NCI);   Array BioPharma
Not yet recruiting

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Pediatric Long-Term Follow-up and Rollover Study

Conditions:   Diffuse Astrocytoma;   Anaplastic Astrocytoma;   Astrocytoma;   Oligodendroglioma, Childhood;   Anaplastic Oligodendroglioma;   Glioblastoma;   Pilocytic Astrocytoma;   Giant Cell Astrocytoma;   Pleomorphic Xanthoastrocytoma;   Anaplastic Pleomorphic Xanthoastrocytoma;   Angiocentric Glioma;   Chordoid Glioma of Third Ventricle;   Gangliocytoma;   Ganglioglioma;   Anaplastic Ganglioglioma;   Dysplastic Gangliocytoma of Cerebrellum;   Desmoplastic Infantile Astrocytoma and Ganglioglioma;   Papillary Glioneuronal Tumor;   Rosette-forming Glioneurona Tumor;   Central Neurocytoma;   Extraventricular Neurocytoma;   Cerebellar Liponeurocytoma;   Neurofibromatosis Type 1
Interventions:   Drug: dabrafenib;   Drug: trametinib
Sponsor:   Novartis Pharmaceuticals
Not yet recruiting

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Memory Perception Assessment in Central/Non-central Nervous System Cancers and HIV

Conditions:   Glioblastoma;   Glioma;   Breast Cancer;   Hiv;   Healthy
Intervention:   Other: QMRP questionnaire
Sponsor:   Institut du Cancer de Montpellier - Val d'Aurelle
Recruiting

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Ultrasound Elastography and Ultrasentive Doppler for Surgery of Brain Tumors

Condition:   Brain Tumor, Primary
Intervention:   Procedure: brain tumor resection
Sponsors:   University Hospital, Tours;   Institut National de la Santé Et de la Recherche Médicale, France
Recruiting

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FBY PET/CT in Patients With Brain Tumors

Condition:   Brain Tumor
Intervention:   Diagnostic Test: FBY-PET Examination Group: Patients receive FBY-PET examination after entrance
Sponsors:   Peking Union Medical College Hospital;   Peking University;   Beijing Cancer Hospital
Recruiting

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Intraoperative Fluorescence of Ganglogliomas and Neuroepithelial Dysembryoplastic Tumors

Condition:   Surgical Procedure, Unspecified
Intervention:  
Sponsor:   Rennes University Hospital
Completed

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Abemaciclib in Patients With Oligodendroglioma

Condition:   Oligodendroglioma, Adult
Intervention:   Drug: Abemaciclib 200 MG
Sponsor:   University of Pennsylvania
Recruiting

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A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

Condition:   Glioblastoma
Interventions:   Drug: Temozolomide;   Drug: Lomustine;   Drug: Regorafenib;   Radiation: Radiation
Sponsor:   Global Coalition for Adaptive Research
Not yet recruiting

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AXL Inhibitor BGB324 in Treating Participants With Recurrent Glioblastoma Undergoing Surgery

Condition:   Brain and Central Nervous System Tumors
Interventions:   Drug: BGB 324 (before surgery);   Drug: BGB 324 (after surgery)
Sponsors:   Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins;   National Cancer Institute (NCI)
Not yet recruiting

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