Eosinophilic Esophagitis (EoE) Clinical Trials


Efficacy, Safety, and Pharmacokinetics of APT-1011 in Subjects With Eosinophilic Esophagitis (EoE) (FLUTE)

Eosinophilic esophagitis (EoE) is an inflammatory disease of the esophagus, characterized by eosinophilic infiltration and gastrointestinal symptoms. Swallowed, topically acting corticosteroids, such as fluticasone, appear to be effective in resol...

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Eosinophilic Esophagitis Clinical Therapy Comparison Trial

Eosinophilic Esophagitis (EoE) is a disorder in which a type of white blood cell (eosinophil) involved in allergic reactions, enter and cover the walls of the esophagus (food pipe). As a result, the esophagus becomes swollen and blocked makin...

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Budesonide Versus Fluticasone for Treatment of Eosinophilic Esophagitis

Purpose: To determine whether oral viscous budesonide (OVB) or fluticasone metered dose inhaler (MDI) most effectively treats EoE by improving histologic findings and symptoms, which medication provides a more durable treatment response, and wheth...

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Cytosponge and Dietary Therapy in EoE

This study is being done to see if the investigators can use only the cytosponge ( A 10 minute, in office procedure that does not require sedation) to replace the 6-10 endoscopies routinely perform during dietary restriction and food reintroductio...

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Oral Cromolyn Sodium for the Treatment of Eosinophilic Esophagitis

Condition:   Eosinophilic Esophagitis
Interventions:   Drug: oral cromolyn sodium;   Drug: Placebo
Sponsor:   University of Tennessee
Unknown status - verified March 2015

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The Effect of Sucralfate Slurry in Patients With Eosinophilic Esophagitis

Condition:   Eosinophilic Esophagitis
Interventions:   Drug: Sucralfate;   Procedure: Intraluminal Impedance;   Device: Intraluminal Impedance
Sponsor:   Mayo Clinic
Active, not recruiting - verified March 2016

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Esophageal Absorption in EoE

Condition:   Eosinophilic Esophagitis
Intervention:   Other: D-xylose
Sponsor:   Mayo Clinic
Terminated - verified July 2016

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Fibrostenotic Eosinophilic Esophagitis: Assessment Tools

Condition:   Eosinophilic Esophagitis
Intervention:  
Sponsor:   University of Colorado, Denver
Recruiting - verified November 2016

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Esophageal Motility in Eosinophilic Esophagitis Evaluated by High Resolution Manometry.

Condition:   Eosinophilic Esophagitis
Intervention:   Device: High resolution manometry (HRM)
Sponsor:   Technische Universität München
Unknown status - verified January 2015

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EoE(Eosinophilic Esophagitis)

Conditions:   Eosinophilic Esophagitis;   Dysphagia
Interventions:   Procedure: Eosinophilic Esophagitis with Dysphagia;   Procedure: Eosinophilic Esophagitis with Dysphagia
Sponsor:   University of Michigan
Completed - verified December 2016

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Mucosal Impedance and Eosinophilic Esophagitis

Condition:   Eosinophilic Esophagitis
Intervention:   Device: Mucosal Impedance
Sponsor:   Mayo Clinic
Active, not recruiting - verified September 2016

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Intestinal Permeability in Response to Treatment in Eosinophilic Esophagitis Patients

Condition:   Eosinophilic Esophagitis
Intervention:   Other: Absorbable sugars
Sponsor:   Mayo Clinic
Completed - verified June 2014

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Prevalence of Food Allergies in a Cohort of Adult Patients With Eosinophilic Esophagitis

Condition:   In This Study, we Aim to Determine the Prevalence of Food Allergies in a Cohort of Adults With Eosinophilic Esophagitis.
Intervention:  
Sponsor:   University of South Florida
Completed - verified October 2014

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A Six Month, Safety Follow-up Study in Eosinophilic Esophagitis Subjects Who Completed Study PR-021

Condition:   Eosinophilic Esophagitis
Interventions:   Drug: EUR-1100;   Drug: Placebo
Sponsor:   Forest Laboratories
Completed - verified February 2017

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The Frequency of Eosinophilic Esophagitis in Patients With Heartburn That is Refractory to Proton Pump Inhibitors

Conditions:   Gastroesophageal Reflux Disease;   Eosinophilic Esophagitis
Intervention:   Drug: Treat with lansoprazole 30 mg BID for 2 weeks, endoscopic examination with esophageal biopsy for patients with persistent symptoms
Sponsors:   Dallas VA Medical Center;   TAP Pharmaceutical Products Inc.
Terminated - verified February 2013

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Eosinophilic Esophagitis Databank

Conditions:   Esophagitis;   Eosinophilic Esophagitis
Intervention:  
Sponsors:   National Institute of Allergy and Infectious Diseases (NIAID);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Completed - verified November 2016

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Confocal Laser Endomicroscopy in Patients With Eosinophilic Esophagitis

Condition:   Eosinophilic Esophagitis.
Intervention:   Device: Confocal laser endomicroscopy
Sponsor:   University of Erlangen-Nürnberg Medical School
Unknown status - verified January 2013

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Exhaled Nitric Oxide as a Biomarker of Disease Activity in Eosinophilic Esophagitis

Condition:   Eosinophilic Esophagitis
Intervention:   Device: NIOX MINO® Airway Inflammation Monitor
Sponsor:   Tufts Medical Center
Completed - verified February 2012

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Fluticasone Versus Esomeprazole to Treat Eosinophilic Esophagitis

Condition:   Eosinophilic Esophagitis
Interventions:   Drug: Swallowed fluticasone;   Drug: Esomeprazole
Sponsor:   Walter Reed Army Medical Center
Completed - verified March 2013

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Dose-Ranging Study of Oral Viscous Budesonide in Pediatrics With Eosinophilic Esophagitis

Condition:   Eosinophilic Esophagitis (EoE)
Interventions:   Drug: budesonide;   Drug: placebo
Sponsor:   Shire
Completed - verified March 2014

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