Congenital Heart Defect (CHD) Clinical Trials

Clinical Study Assessing the Efficacy and Safety of Macitentan in Fontan-palliated Subjects

Condition:   Congenital Heart Disease
Interventions:   Drug: Macitentan 10 mg;   Drug: Placebo
Sponsor:   Actelion
Not yet recruiting - verified September 2017

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Role of Sildenafil for Fontan Associated Liver Disease (SiFALD) Study

Conditions:   Cirrhosis;   Congenital Heart Disease
Interventions:   Drug: Sildenafil;   Drug: Placebo
Sponsor:   Mayo Clinic
Recruiting - verified September 2017

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Multicenter Trial of Congenital Pulmonic Valve Dysfunction Studying the SAPIEN 3 THV With the Alterra Adaptive Prestent

Conditions:   Pulmonary Disease;   Transpulmonary Valve Replacement;   Pulmonary Stenosis;   TPVR;   Tetralogy of Fallot;   Congenital Heart Disease
Intervention:   Device: Edwards Alterra Adaptive Prestent with SAPIEN 3 THV
Sponsor:   Edwards Lifesciences
Recruiting - verified September 2017

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Xeltis Bioabsorbable Pulmonary Valved Conduit Early Feasibility Study

Condition:   Heart Defect, Congenital
Intervention:   Device: Xeltis Bioabsorbable Pulmonary Valved Conduit
Sponsor:   Xeltis
Recruiting - verified September 2017

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A Study of the Safety and Pharmacokinetics of Apixaban Versus Vitamin K Antagonist (VKA) or Low Molecular Weight Heparin (LMWH) in Pediatric Subjects With Congenital or Acquired Heart Disease Requiring Anticoagulation

Condition:   Thrombosis
Interventions:   Drug: Apixaban;   Drug: Vitamin K Antagonist (VKA);   Drug: Low Molecular Weight Heparin (LMWH)
Sponsors:   Bristol-Myers Squibb;   Pediatric Heart Network;   Pfizer
Recruiting - verified September 2017

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Real-time MRI Right Heart Catheterization Using Passive Catheters

Conditions:   Caridovascular Disease;   Congenital Heart Disease;   Pulmonary Hypertension
Interventions:   Device: Balloon catheter for right heart catheterization;   Drug: Gadopentate Dimeglumine (Gadolinium); Contrast Agent;   Procedure: Right Heart Catheterization;   Procedure: Cardiac Real-time MRI;   Procedure: Vascular Hemostasis
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting - verified September 1, 2017

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