What are the treatment options for chronic myelogenous leukemia (CML)? 

The type of treatment a patient receives highly depends on the severity of the condition. Some patients with CML notice improvements with one method of treatment, while others are treated with a combination. Availabe treatment options include: 
 
 
Targeted drug therapy works by targeting specific abnormalities in myelogenous leukemia cells. This form of treatment is often combined with chemotherapy drugs. 
 
  • Tyrosine kinase inhibitor therapy blocks tyrosine kinase - the enzyme that causes stem cells to develop into more white blood cells (granulocytes) than the body needs. 
 
Chemotherapy refers to the use of chemical agents whose main effect is either to kill or slow the reproduction of rapidly multiplying myelogenous leukemia cells. This results in shrinkage or cancer cell death. Drugs can be delivered through a vein in your arm (intravenously), or they can be taken orally
 
 
Biological therapy (immunotherapy) uses drugs and vaccines to harness the immune system’s natural ability to fight cancer, in the same way it fights off infections.
 
 
Bone marrow stem cell transplants use strong chemotherapy drugs to kill the stem cells in your bone marrow that are creating diseased granulocytes. Then healthy adult blood stem cells from a donor are infused into your blood, where they travel to your bone marrow and begin making healthy blood cells.
 
 
Splenectomy is surgery to remove the spleen. 
 
 
 
 
chronic myelogenous leukemia treatment
 
 
 

Sources
  • "Chronic Myelogenous Leukemia." Mayo Clinic. Mayo Foundation for Medical Education and Research, 26 May 2016. Web. 07 July 2017.
  • "Chronic Myelogenous Leukemia." Chronic Myelogenous Leukemia. Cleveland Clinic, n.d. Web. 07 July 2017.
  • Hill, Michael. "Chronic Myelogenous Leukemia." Johns Hopkins Sidney Kimmel Comprehensive Cancer Center. Johns Hopkins Health System, 04 Feb. 2016. Web. 07 July 2017.

 

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